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South_Africa/PPD_00BCRMZ.1/2025-09-30
J. Maritz, D. Goedhals, J. Pekeur, T. Maponga, M. Claassen, T. Stander, G. van Zyl, W. Preiser, L. M. Hofstra, L. Chabuka, K. W. Liedeman, S. De Villiers, V. Wentzel, L. Singh, T. Ramakutoane, H. Tegally, E. Wilkinson & T. de Oliveira

S, Cape Town, Western Cape

Sample details

Collection date
2025-09-30
Sampling location
South Africa (Western Cape; Cape Town; Cape Town)
Isolate name
hMPV/B/SouthAfrica/PATH-CERI-C070888/2025

Data use terms

Data use terms
OPEN

Lineage

Lineage
B2

INSDC

INSDC accession
BioProject accession
BioSample accession
NCBI release date
2026-02-28
NCBI update date
2026-03-01

Host

Submission details

Submission ID
OZ414740.1
Date submitted
2026-03-01 06:36:33 UTC
Date released
2026-03-01 06:45:58 UTC
Earliest release date
2026-02-28

Alignment and QC

Length
13264 (100%)
# of SNPs
2473
# of inserted bases
23
# of deleted bases
109
# of frame shifts
2
# of stop codons
2
Frame shifts
G:149-159(nt:6691-6723),G:207-223(nt:6865-6915)
Stop Codons
SH:178,G:227

Nucleotide mutations

Mutations called relative to the NC_039199.1 reference

Substitutions

  • G11A
  • A20C
  • T26C
  • G34A
  • G36A
  • G63A
  • T70C
  • A72G
  • C78T
  • G81A
  • G99A
  • G105A
  • G126A
  • A132C
  • A162G
  • A168G
  • G177T
  • A189G
Deletions

24, 2934, 3006, 4684-4722, 6025-6027, 6112-6114, 6166, 6196, 6210-6215, 6864, 6916, 6917, 6977-6984, 7009-7015, 7034-7037, 7144-7147, 13188-13191, 13207, 13208, 13285-13304, 13313
Insertions

ins_2981:C, ins_5813:AGA, ins_6690:A, ins_6723:AAGGAAAAGAA, ins_6767:ACT, ins_7065:TT, ins_7080:T, ins_13230:G

Amino acid mutations

Mutations called relative to the NC_039199.1 reference

Substitutions

F

  • F:V6M
  • F:F9I
  • F:A61T
  • F:R82K
  • F:V122I
  • F:T135N
  • F:N139G
  • F:K143T
  • F:D167E
  • F:R175S
  • F:T223N
  • F:N233Y
  • F:F258I
  • F:D280N
  • F:V286I
  • F:G294E
  • F:K296D
  • F:Q312K

G

  • G:K4R
  • G:T10A
  • G:L14F
  • G:R17K
  • G:V18M
  • G:V22I
  • G:A23R
  • G:R24N
  • G:F28Y
  • G:K29R
  • G:S32T
  • G:V34I
  • G:I38L
  • G:T40A
  • G:I43M
  • G:Y48F
  • G:N52D
  • G:K54A

L

  • L:L4F
  • L:N5C
  • L:N42K
  • L:A46S
  • L:I50V
  • L:K61R
  • L:N65M
  • L:S66T
  • L:I75V
  • L:V79I
  • L:V89T
  • L:T109S
  • L:N113S
  • L:S123T
  • L:D127N
  • L:S132N
  • L:S141V
  • L:K162R

M

  • M:I23V
  • M:E103D
  • M:E111D
  • M:T156I
  • M:K237R
  • M:T241S

M2-1

  • M2-1:I37L
  • M2-1:R52K
  • M2-1:S88G
  • M2-1:V108I
  • M2-1:V130I
  • M2-1:R149K
  • M2-1:K160R
  • M2-1:A169T
  • M2-1:E170D

M2-2

  • M2-2:E18K
  • M2-2:V22K
  • M2-2:V28A
  • M2-2:D37E
  • M2-2:A41T
  • M2-2:N55S

N

  • N:A54T
  • N:A57T
  • N:S71C
  • N:R96K
  • N:I103G
  • N:N106S
  • N:D110E
  • N:A136V
  • N:M201V
  • N:D212E
  • N:H220Y
  • N:K356R
  • N:V385M
  • N:S389N
  • N:N391D

P

  • P:L19I
  • P:R28K
  • P:K29R
  • P:P30S
  • P:S35T
  • P:I39V
  • P:N44T
  • P:V46I
  • P:K60R
  • P:P61S
  • P:T62S
  • P:I63T
  • P:S65L
  • P:T72A
  • P:K74S
  • P:G75S
  • P:E81T
  • P:I82E

SH

  • SH:I2K
  • SH:T17N
  • SH:H18Q
  • SH:D25N
  • SH:V30L
  • SH:V33A
  • SH:L44F
  • SH:I50V
  • SH:I61A
  • SH:S64L
  • SH:T66N
  • SH:S73T
  • SH:S74K
  • SH:S75L
  • SH:V80T
  • SH:T82I
  • SH:T84P
  • SH:T85I
Deletions

G

G:201, G:224

SH

SH:175
Insertions

G

ins_G:173:AA, ins_G:180:NQT

SH

ins_SH:108:R

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